Morphology-based selection from available euploid blastocysts induces male-skewed sex proportion in the offspring

ConclusionBlastocyst features associated with a skewed sex proportion towards XY embryos, such as biopsy on day 5 and top quality TE, are also parameters used for selecting euploid embryos for SET. Therefore, our data suggest that morphology-based embryo selection represents a strong factor responsible for a skewed male sex proportion at birth in PGT-A cycles.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research