The role of Notch ligand, Delta-like ligand  4 (DLL4), in cancer angiogenesis—implications for therapy

ConclusionDLL4 seems to be a  promising target in anti-cancer therapy. Nevertheless, the careful evaluation of adverse effects on normal physiological processes in relation to therapeutic doses of anti-DLL4 drugs will be significant for advancement of DLL4 blocking agents in clinical oncology.
Source: European Surgery - Category: Surgery Source Type: research