Some Supplements May Lower Risk for SARS-CoV-2 Positivity

TUESDAY, April 20, 2021 -- The use of probiotics, omega-3 fatty acids, multivitamins, and vitamin D supplements is associated with a reduction in the risk for testing positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), at...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Comb Chem High Throughput Screen. 2021 Nov 30. doi: 10.2174/1386207325666211130140923. Online ahead of print.ABSTRACTInfection by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) provokes acute inflammation due to extensive replication of the virus in the epithelial cells of the upper and lower respiratory system. The mammalian target of rapamycin (mTOR) is a l signalling protein with critical functions in cell growth, metabolism, and proliferation. It is known for its regulatory functions in protein synthesis and angiogenesis cascades. The structure of mTOR consists of two distinct complexes (mTORC1 and mT...
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Source Type: research
GISAID hosts a vast, open database of genomic sequences of SARS-CoV-2 coronavirus samples, and medical laboratory scientists in countries across the globe are contributing Clinical laboratories around the world have been contributing to the global scientific community’s database of knowledge about SARS-CoV-2, the coronavirus that caused the COVID-19 pandemic, and its variants, through an ingenious […] The post More Countries Are Now Capable of Genome Sequencing and Contributing to Global COVID-19 GISAID Database than Ever Before appeared first on Dark Daily.
Source: Dark Daily - Category: Laboratory Medicine Authors: Tags: Digital Pathology International Laboratory News Laboratory Instruments & Laboratory Equipment Laboratory Pathology Laboratory Resources Laboratory Testing Molecular Diagnostics, Genetic Testing, Whole Gene Sequencing Precision Medicine ACE Source Type: news
In this study, we characterized the haplotype and sub-haplotype diversity of SARS-CoV-2 global variants in January-March and the areas with low and high COVID19 vaccination rates in May 2021 by analyzing viral proteome of complete genome sequences published. Phylogenetic tree analysis of the proteomes of SARS-CoV-2 variants with Neighbor-Joining and Maximum Parsimony methods indicated that haplotype 2 variant with nsp12 P323L and Spike D614G was dominant (98.81%), including new sub-haplotypes 2A_1 to 2A_3, 2B_1 to 2B_3, and 2C_1 to 2C_2 emerged post-one-year COVID-19 outbreak. In addition, the profiling of sub-haplotypes i...
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Source Type: research
CONCLUSIONS: Bronchoscopy in patients with COVID-19 results in a significant change in patient management. Transmission of SARS-CoV-2 seems to be low with consistent use of appropriate personal protective equipment by health-care workers. Therefore, bronchoscopic evaluation should be considered for all diagnostic and therapeutic indications in this patient population.PMID:34848547 | DOI:10.4187/respcare.09405
Source: Respiratory Care - Category: Respiratory Medicine Authors: Source Type: research
AbstractTwo mRNA coronavirus disease 2019 (COVID-19) vaccines, BNT162b2 and mRNA-1273, are effective to prevent infection of SARS-CoV-2 and to prevent developing severe COVID-19 in the general population. Although BNT162b2 elicits CD4+ and CD8+ T-cell responses, mRNA-1273 induces poor CD8+ responses. Therefore, the effect of mRNA-1273 vaccine might be weak in patients treated with anti-CD20 monoclonal antibodies, showing a marked decrease of anti-SARS-CoV-2 antibody production after COVID-19 vaccination. We discuss a selection of mRNA vaccines based on their different CD8+ T-cell functions in multiple sclerosis patients wi...
Source: Clinical and Experimental Neuroimmunology - Category: Neurology Authors: Tags: COMMENTARY Source Type: research
Contributors : Michelle Meyer ; Yuan Wang ; Darin Edwards ; Gregory R Smith ; Aliza B Rubenstein ; Palaniappan Ramanathan ; Chad E Mire ; Colette Pietzsch ; Xi Chen ; Yongchao Ge ; Wan S Cheng ; Carole Henry ; Angela Woods ; Ling Z Ma ; Guillaume Stewart-Jones ; Kevin W Bock ; Mahnaz Minai ; Bianca M Nagata ; Sivakumar Periasamy ; Pei Y Shi ; Barney S Graham ; Ian N Moore ; Irene Ramos ; Olga G Troyanskaya ; Elena Zaslavsky ; Andrea Carfi ; Stuart C Sealfon ; Alexander BukreyevSeries Type : Expression profiling by high throughput sequencingOrganism : Mesocricetus auratusmRNA-1273, an mRNA-based vaccine for severe acute res...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mesocricetus auratus Source Type: research
ConclusionIn conclusion, SARSCoV-2 infection can induce various spectrum of autoimmune encephalitis. It is a major concern since there is very limited long-term study on the topic. Hence, this review aims to elucidate on the potential long-term complication of SARS-CoV-2 infection and hopefully to improve the management and prognosis of COVID-19.
Source: Neurological Sciences - Category: Neurology Source Type: research
accio U. Rajendra Acharya The global pandemic of coronavirus disease (COVID-19) has caused millions of deaths and affected the livelihood of many more people. Early and rapid detection of COVID-19 is a challenging task for the medical community, but it is also crucial in stopping the spread of the SARS-CoV-2 virus. Prior substantiation of artificial intelligence (AI) in various fields of science has encouraged researchers to further address this problem. Various medical imaging modalities including X-ray, computed tomography (CT) and ultrasound (US) using AI techniques have greatly helped to curb the COVID-19 outbrea...
Source: Sensors - Category: Biotechnology Authors: Tags: Review Source Type: research
In conclusion, the current findings explored the key features of the NSP13 WT and its mutant complexes, which can be used to design structure-based inhibitors against the SARS-CoV-2 new variants to rescue the host immune system.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
While no cases of the new coronavirus variant, Omicron, have been reported in the U.S. yet, it’s only a matter of time. In fact, Dr. Anthony Fauci, chief medical advisor on COVID-19 to President Biden, says it’s likely the virus is already in the country, given how much travel is occurring between countries as pandemic restrictions have started to lift in recent months. Even if the variant were here, could existing tests tell if someone were infected by it? Testing experts say yes and no. The majority of tests used by commercial and public health labs can detect SARS-CoV-2, but they can’t confirm which ve...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
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