Rituximab-induced Hypogammaglobulinemia and Infection Risk in Pediatric Patients

IgG hypogammaglobulinemia was frequent in children receiving rituximab (40%), and was associated with an increased risk of serious infections. Physician-diagnosed PID unmasked by rituximab was found in 4.3% (9/207) of the cohort.

Source: Journal of Allergy and Clinical Immunology - April 13, 2021 Category: Allergy & Immunology Authors: Roxane Labrosse, Sara Barmettler, Beata Derfalvi, Annaliesse Blincoe, Guilhem Cros, Jonathan Lacombe-Barrios, Julie Barsalou, Nancy Yang, Nora Alrumayyan, Jan Sinclair, Mei-Sing Ong, Carlos A. Camargo, Jolan Walter, Elie Haddad Source Type: research