Standardized Uptake Value for 18F-Fluorodeoxyglucose is a Marker of Inflammatory State and Immune Infiltrate in Cervical Cancer

CONCLUSIONS: SUVmax is a prognostic marker in cervical cancer that is associated with activation of inflammatory pathways and tumor infiltration of myeloid-derived immune cells, particularly macrophages. Macrophages contribute to changes in cervical cancer glucose metabolism.PMID:33820781 | DOI:10.1158/1078-0432.CCR-20-4450

Source: Clinical Cancer Research - April 6, 2021 Category: Cancer & Oncology Authors: John M Floberg Jin Zhang Naoshad Muhammad Todd A DeWees Matthew Inkman Kevin Chen Alexander J Lin Ramachandran Rashmi Kay Jayachandran Brian T Edelson Barry A Siegel Farrokh Dehdashti Perry W Grigsby Stephanie Markovina Julie K Schwarz Source Type: research