Primary pigmented nodular adreno-cortical disease

Cushing's syndrome can cause significant morbidity; effective treatment requires integrated clinical, biochemical, and radiological assessments to reach an accurate diagnosis. Primary pigmented nodular adreno-cortical disease (PPNAD) is an uncommon cause of ACTH-independent Cushing's. Diagnosis can be challenging, in particular where the radiological findings are normal or suggestive of a unilateral process. The condition is very commonly associated with Carney complex and referral for evaluation by a clinical genetics team is essential.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Short Case Source Type: research