Patient ‐reported sleep outcomes lack association with mucosal eosinophilia or neutrophilia in patients with chronic rhinosinusitis undergoing functional endoscopic sinus surgery

ConclusionChronic inflammation has been hypothesized to play a pathophysiologic role in sleep dysfunction associated with CRS. This study suggests that in patients with medically refractory CRS, evidence of mucosal eosinophilia and neutrophilia lack strong associations with patient ‐reported sleep dysfunction or improvements in sleep quality after FESS, overall. However, neutrophilia may impact sleep latency and efficacy in patients with CRSsNP.

Source: International Forum of Allergy and Rhinology - March 23, 2021 Category: Allergy & Immunology Authors: Nyssa Fox Farrell, Jess C. Mace, David A. Sauer, Andrew J. Thomas, Mathew Geltzeiler, Kara Y. Detwiller, Jeremiah A. Alt, Timothy L. Smith Tags: ORIGINAL ARTICLE Source Type: research