Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum

Silybum marianum (SM) is an herbal product with cytoprotective and antioxidant properties. We have previously demonstrated that SM ameliorates ventricular remodeling and improves cardiac performance. Here, we evaluated whether SM could exert beneficial effects against cardiac lipotoxicity in a pig model of closed-chest myocardial infarction (MI).

Source: Atherosclerosis - March 27, 2021 Category: Cardiology Authors: Gemma Vilahur, Pablo Sutelman, Guiomar Mendieta, Soumaya Ben-Aicha, Mar ía Borrell, Esther Peña, Javier Crespo, Laura Casaní, Lina Badimon Source Type: research