The Alterations in Methylene Blue/Light-Treated Frozen Plasma Proteins Revealed by Proteomics

Conclusion: This comparative proteomics study revealed that some significantly modified proteins occur in MB-FP, such as C1R, ITI-H4, KRT1, HPX, FGG, and TTR. Our findings provide more theoretical data for using MB-FP in transfusion medicine. However, the relevance of the data for the transfusion of methylene blue/light-treated plasma remains unclear. The exact modification of these proteins and the effects of these modified proteins on their functions and their effects in clinical plasma infusion need to be further studied.Transfus Med Hemother

Source: Transfusion Medicine and Hemotherapy - March 23, 2021 Category: Hematology Source Type: research