Hydatidiform mole diagnostics using circulating gestational trophoblasts isolated from maternal blood

ConclusionOur results show that it is possible to isolate and analyze circulating gestational trophoblasts originating in a pregnancy without maternal nuclear genome. For diagnosing gestational trophoblastic diseases, genotyping circulating gestational trophoblasts appears to be superior to analysis of cell ‐free DNA.

Source: Molecular Genetics & Genomic Medicine - March 16, 2021 Category: Genetics & Stem Cells Authors: Lone Sunde, Ripudaman Singh, Katarina Ravn, Palle Schelde, Estrid St æhr Hansen, Niels Uldbjerg, Isa Niemann, Lotte Hatt Tags: ORIGINAL ARTICLE Source Type: research