Comparison between Abbott m2000 RealTime and Alinity m STI systems for detection of Chlamydia trachomatis , Neisseria gonorrhoeae , and Mycoplasma genitalium

AbstractThe new Abbott Alinity m STI Assay was compared with Abbott m2000 RealTime PCR. ForChlamydia trachomatis, 26 (7.5%) of 347 samples were positive in the Alinity assay and 24 (6.9%) in the m2000 assay. Corresponding figures forNeisseria gonorrhoeae were 23 (6.6%) and 17 (4.9%). ForMycoplasma genitalium, 22 (7.9%) of 279 samples were positive in the Alinity assay and 18 (6.5%) in the m2000 assay, for which DNA extraction was performed on an m2000sp instrument combined with in-house real-time PCR. The Alinity assay has at least the same sensitivity as the m2000 assay. The specificity was evaluated by discrepancy analysis.
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research