Tripartite motif-containing protein 6 facilitates growth and migration of breast cancer through degradation of STUB1

In conclusion, TRIM6 contributed to breast cancer progression through ubiquitination-dependent proteasomal degradation of STUB1 and provocation of YAP1 pathway, providing potential therapeutic target for breast cancer.

Source: European Journal of Histochemistry - January 20, 2021 Category: Biomedical Science Authors: Chuanchao Wei, Jiayue Wu, Weiyan Liu, Jingfeng Lu, Hongchang Li, Benjun Hai Source Type: research