Olfactory cleft mucus inflammatory proteins in CRS: a case ‐control study

ConclusionThis study confirmed that OC inflammatory proteins vary both by disease phenotype and in their association with OD. Type 2 inflammatory mediators are increased in CRS, especially within the CRSwNP group. However, a substantial proportion of CRSsNP also express type 2 inflammatory mediators. Further research is necessary to understand the complex roles OC mucous inflammatory proteins might play in defining endotype and in impacting CRS ‐related OD. ©2021 ARSAAOA, LLC.

Source: International Forum of Allergy and Rhinology - February 25, 2021 Category: Allergy & Immunology Authors: Timothy L. Smith, Rodney J. Schlosser, Zachary M. Soler, Jess C. Mace, Jose L. Mattos, Vijay R. Ramakrishnan, Daniel M. Beswick, Jeremiah A. Alt, Jennifer K. Mulligan Tags: ORIGINAL RESEARCH ARTICLE Source Type: research