Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

Linezolid is administered as a fixed dose to all patients despite evidence of overexposure and thrombocytopenia in renal impairment. The aims of this study were to evaluate the risk of thrombocytopenia and the...

Source: BMC Clinical Pharmacology - March 4, 2021 Category: Drugs & Pharmacology Authors: Hitoshi Kawasuji, Yasuhiro Tsuji, Chika Ogami, Kou Kimoto, Akitoshi Ueno, Yuki Miyajima, Koyomi Kawago, Ippei Sakamaki and Yoshihiro Yamamoto Tags: Research article Source Type: research