Development and validation of a biomonitoring method to measure As, Cr, and Ni in human urine samples by ICP-UCT-MS

We present our rigorous validation of the method selectivity and accuracy using National Institute of Standards and Technology (NIST) Standard Reference Materials (SRM), precision using in-house prepared quality control materials, and a discussion of the use of a modified UCT, a BioUCell, to address an ion transmission phenomenon we observed on the NexION 300 platform when using higher elemental concentrations and high cell gas pressures. The rugged method detection limits, calculated from measurements in more than 60 runs, for As, Cr, and Ni are 0.23 μg L-1, 0.19 μg L-1, and 0.31 μg L-1, respectively.PMID:33621861 | DOI:10.1016/j.ijheh.2021.113713

Source: International Journal of Hygiene and Environmental health - February 23, 2021 Category: Environmental Health Authors: Deanna R Jones Jeffery M Jarrett Danielle Stukes Adam Baer Megan McMichael Kristen Wallon Ge Xiao Robert L Jones Source Type: research