Molecular profile of KRAS G12C-mutant colorectal and non-small-cell lung cancer

KRAS is the most frequently mutated oncogene in cancer, however efforts to develop targeted therapies have been largely unsuccessful. Recently, two small-molecule inhibitors, AMG 510 and MRTX849, have shown promi...

Source: BMC Cancer - February 25, 2021 Category: Cancer & Oncology Authors: Luiz Henrique Araujo, Bianca Mendes Souza, Laura Rabelo Leite, Sabrina A. F. Parma, Nat ália P. Lopes, Frederico S. V. Malta and Maíra C. M. Freire Tags: Research article Source Type: research