Signal transduction without signal -- receptor clusters can direct cell movement

(Goethe University Frankfurt) Whether we smell, taste or see, or when adrenaline rushes through our veins, all of these signals are received by our cells via a specific group of receptor proteins called G protein-coupled receptors, which transmit signals to the inside of the cell. Biochemists at Goethe University Frankfurt and the University of Leipzig have now discovered that such receptors can also produce signals even in the absence of an external stimulus: For certain receptors clustering is apparently sufficient.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news