Effect of vitamin C, thiamine, and hydrocortisone on ventilator- and vasopressor-free Days in patients with sepsis

RCT (n=501) found no significant increase of ventilator- and vasopressor-free days with vitamin C, thiamine and hydrocortisone treatment vs placebo in critically ill patients with sepsis. Trial terminated early for administrative reasons and may have been underpowered.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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The cancer organization today largely reinstated its former advice that men with low-risk prostate cancer be offered active surveillance as the lone'preferred'initial treatment option.News Alerts
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news
Applications for the open CEO position will be accepted through Jan. 14, 2022.
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
No abstract available
Source: The Journal of ECT - Category: Psychiatry Tags: Commentaries Source Type: research
Conclusions Our results confirm earlier prospective and retrospective data regarding the efficacy and importance of C/M-ECT as relapse prevention. After treatment discontinuation, close monitoring of early warning signs for relapse is crucial, especially in the first few months. With the COVID-19 pandemic continuing, our data provide an indication of the necessity to ensure adequate care and access to ECT not only for the acutely ill but also for the vulnerable patients who are depending on C/M-ECT.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions Among patients who begin treatment with RUL-BP ECT, more than 60% use exclusively those parameters throughout their acute course.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions Concurrent lithium administration during the initial acute ECT course was not associated with differential cognitive or symptomatic outcomes. Lithium administration should not be a contraindication for appropriate acute ECT treatment in patients. Larger controlled studies to confirm these findings are warranted.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions The association between the duration of postictal burst suppression and reorientation time after ECT in this sample suggests that (not only the efficacy but also the) cognitive adverse effects of ECT might be related to the extent of postictal central inhibition after the termination of the seizure.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions The ECT treatment of affective disorders was not associated with an increased long-term risk of developing dementia compared with in-patients with affective disorders not treated with ECT.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions Although limited by the open-label, nonrandomized design, FEAST showed comparable effects on suicidal ideation when compared with routine use of UB-RUL ECT. These results are encouraging and support the need for further research and a noninferiority trial.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions Results suggested that Glx levels could be a predictor of remission. Studies with larger samples should explore neurochemical correlates of ECT in unipolar MDD.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
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