Proliferating Pilar Tumors: Can Immunohistochemistry Differentiate Benign and Malignant Forms?

Conclusions: Our study includes the largest group of patients in whom image analysis of p53, Ki67, and p27 has been used to try to separate benign from malignant lesions. Although there were no significant differences regarding Ki67 and p53, malignant lesions have a statistically lower expression of p27. Further studies may be needed to determine the clinical usefulness of image analysis in this differential diagnosis.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Original Study Source Type: research