Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

The ongoing global malaria eradication campaign requires development of potent, safe, and cost-effective drugs lacking cross-resistance with existing chemotherapies. One critical step in drug development is se...

Source: Malaria Journal - February 19, 2021 Category: Infectious Diseases Authors: Yizhe Chen, Fangyi Zhu, Jared Hammill, Gloria Holbrook, Lei Yang, Burgess Freeman, Karen L. White, David M. Shackleford, Kathleen G. O ’Loughlin, Susan A. Charman, Jon C. Mirsalis and R. Kiplin Guy Tags: Research Source Type: research