Distinguishing bacterial versus non-bacterial causes of febrile illness – a systematic review of host biomarkers

Severe and non-severe fevers are a major cause of morbidity and mortality around the world and are one of the primary reasons patients seek healthcare services, both in high-income countries (HICs) and low- and middle-income countries (LMICs) [1]. Fever, also referred to as acute febrile illness (AFI), may result from a variety of infectious or non-infectious causes. However, infections are the leading cause of AFI; particularly in LMICs, where AFI-caused infections represent a major disease burden for children [2, 3].

Source: Journal of Infection - February 18, 2021 Category: Infectious Diseases Authors: B. Leticia Fernandez-Carballo, Camille Escadafal, Emily MacLean, Anokhi J. Kapasi, Sabine Dittrich Source Type: research