The COVID-Kidney Controversy: Can SARS-CoV-2 Cause Direct Renal Infection?

Context: Determining whether SARS-CoV-2 causes direct infection of the kidneys is challenging due to limitations in imaging and molecular tools.Subject of Review: A growing number of conflicting kidney biopsy and autopsy reports highlight this controversial issue.Second Opinion: Based on the collective evidence, therapies that improve hemodynamic stability and oxygenation, or dampen complement activation, are likely to ameliorate acute kidney injury in COVID-19. At this time, whether inhibition of viral infection and replication directly modulates kidney damage is inconclusive.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research