Evaluating key characteristics of ideal colorectal cancer screening modalities: the microsimulation approach

Screening for colorectal cancer (CRC) can effectively reduce CRC incidence and mortality. Besides colonoscopy, detection of biomarkers in stool, blood or serum, including fecal immunochemical test (FIT), ColoGuard, pro Epicolon and PolypDx have recently been advanced. We aimed to identify characteristics of theoretical, highly efficient screening tests and calculated effectiveness and cost-effectiveness of available screening tests.

Source: Gastrointestinal Endoscopy - February 15, 2021 Category: Gastroenterology Authors: Ansgar Deibel, Lu Deng, Chih-Yuan Cheng, Michael Schlander, Tao Ran, Brian Lang, Niklas Krupka, Niko Beerenwinkel, Gerhard Rogler, Reiner Wiest, Amnon Sonnenberg, Jan Poleszczuk, Benjamin Misselwitz Source Type: research