Fine tuning the glycolytic flux ratio of EP-bifido pathway for mevalonate production by enhancing glucose-6-phosphate dehydrogenase (Zwf) and CRISPRi suppressing 6-phosphofructose kinase (PfkA) in Escherichia coli

Natural glycolysis encounters the decarboxylation of glucose partial oxidation product pyruvate into acetyl-CoA, where one-third of the carbon is lost at CO2. We previously constructed a carbon saving pathway, EP...

Source: Microbial Cell Factories - February 2, 2021 Category: Microbiology Authors: Ying Li, He Xian, Ya Xu, Yuan Zhu, Zhijie Sun, Qian Wang and Qingsheng Qi Tags: Research Source Type: research