Predictors for 2-year functional and morphological outcomes of a treat and extend regimen with ranibizumab in patients with diabetic macular edema
Abstract
Purpose: To investigate longer-term functional and morphological outcomes and their predictors in diabetic macular edema (DME) following a treat and extend regimen (TER) without loading dose under ranibizumab.
Methods: Patient data were reviewed and analyzed retrospectively over a period of 24 mo nths after initiation of TER. Best-corrected visual acuity (BCVA), treatment frequency as well as quantitative and qualitative Spectral-domain Optical Coherence Tomography parameters were assessed.
Results: 118 eyes of 87 patients were included. A mean of 9.742.13 injections in the first and 7. 632.29 in the second year were applied. There were significant gains of BCVA and reductions in central retinal thickness from baseline to month 12 and 24 (all p
Source: Ophthalmic Research - Category: Opthalmology Source Type: research
More News: Diabetes | Endocrinology | Eyes | Lucentis | Opthalmology | Ranibizumab Injection | Vitamin A