DUB esterase activity further decodes ubiquitin’s enigma [Biochemistry]

Posttranslational modifications of proteins are often key to understanding their biological function, localization, and fate. In particular, the covalent attachment of ubiquitin, a small 76-amino acid polypeptide, to substrates has attracted recent attention and is being exploited to generate novel drugs capable of removing pathogenic targets in a selective fashion...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biochemistry, Commentaries Commentary Source Type: research