Platelet α-Granule Cargo Packaging and Release are Affected by the Luminal Proteoglycan, Serglycin.

CONCLUSION: The polyanionic proteoglycan SRGN influences α-granule packaging, cargo release, and shedding of platelet membrane proteins.
PMID: 33448622 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - January 15, 2021 Category: Hematology Authors: Chanzu H, Lykins J, Wigna-Kumar S, Joshi S, Pokrovskaya I, Storrie B, Pejler G, Wood JP, Whiteheart SW Tags: J Thromb Haemost Source Type: research