Safety, Pharmacokinetics, and Pharmacodynamics of TQ-A3334, an Oral Toll-Like Receptor 7 Agonist, in Healthy Individuals.

CONCLUSIONS: Oral doses of 0.2-1.8 mg appeared to be safe and tolerated. PD activity was seen at doses ranging from 1.0 to 1.8 mg, indicating its possible future use to treat CHB.
PMID: 33405993 [PubMed - as supplied by publisher]

Source: Expert Opinion on Investigational Drugs - January 8, 2021 Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research