Early life growth and associations with lung function and bronchial hyperresponsiveness at 11-years of age

Low birthweight and being born small-for-gestational age (SGA) are linked to asthma and impaired lung function. Particularly, poor intrauterine growth followed by rapid catch-up growth during childhood may predispose for respiratory disease. Bronchial hyperresponsiveness (BHR) is an essential feature of asthma, but how foetal and early childhood growth are associated with BHR is less studied. Our hypothesis was that children born SGA or with accelerated early life growth have increased BHR and altered lung function at 11-years of age.

Source: Respiratory Medicine - January 7, 2021 Category: Respiratory Medicine Authors: Ingvild Bruun Mikalsen, Thomas Halvorsen, Petur Benedikt Juliusson, Maria Magnus, Wenche Nystad, Trine Stensrud, Ketil St ørdal, Maria Vollsæter, Knut Øymar Tags: Original Research Source Type: research