Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

Two new SARS-CoV-2 lineages with the N501Y mutation in the receptor-binding domain of the spike protein spread rapidly in the United Kingdom. We estimated that the earlier 501Y lineage without amino acid deletionΔ69/Δ70, circulating mainly between early September and mid-November, was 10% (6–13%) more transmissible than the 501N lineage, and the 501Y lineage with amino acid deletionΔ69/Δ70, circulating since late September, was 75% (70–80%) more transmissible than the 501N lineage.

Source: Eurosurveillance - January 7, 2021 Category: Infectious Diseases Authors: Kathy Leung, Marcus HH Shum, Gabriel M Leung, Tommy TY Lam and Joseph T Wu Source Type: research