Exome sequencing identifies a recurrent variant in SERPINA3 associating with hereditary susceptibility to breast cancer
Breast cancer is strongly influenced by hereditary risk factors. Yet, the known susceptibility genes and genomic loci explain only about half of the familial component of the disease. To identify novel breast cancer predisposing gene defects, here we have performed massive parallel sequencing for Northern Finnish breast cancer cases.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Susanna Koivuluoma, Anna Tervasm äki, Saila Kauppila, Robert Winqvist, Timo Kumpula, Outi Kuismin, Jukka Moilanen, Katri Pylkäs Tags: Original Research Source Type: research