Malignant cell characterization via mathematical analysis of bio impedance and optical properties.

Malignant cell characterization via mathematical analysis of bio impedance and optical properties. Electromagn Biol Med. 2020 Dec 27;:1-19 Authors: Hossain S Abstract Diagnosis in the early stage of breast cancer is crucial for the onset of preliminary treatment. Non-radiative bioimpedance measurement in the microwave frequency range can contribute to electrode-medium interface error and the malaise of electrode placement on the patient to take measurements. These reasons account for alternate diagnosis procedure and improved reliability of retrieved mensuration. Non-invasive optical diagnosis in the near infra-red (NIR) and visible light of the electromagnetic range is the shifting paradigm for healthcare diagnosis. An accurate quantitative measurement is unparalleled to circumvent false positives. The focus of this paper is to perform quantitative mathematical analysis for bioimpedance and optical properties for sample breast cancer cells for meticulous interpretation of malignant cell diagnosis. The analytical solution of the Cole-Cole plot, relaxation frequency, and capacitance measurement showed reliability with previous experimental findings. The dissimilitude of the frequency-dependent refractive index measurement of the malignant and healthy cell can be used by clinicians for pronouncement. The diffusion theory is also used to interpret the pathlength of the source light particle and the absorption property of the malignant c...
Source: Electromagnetic Biology and Medicine - Category: Physics Tags: Electromagn Biol Med Source Type: research