HLA-DRB1* and DQB1* allele and haplotype diversity in eight tribal populations: Global affinities and genetic basis of diseases in south India.

CONCLUSION: The HLA immunogenetic study of south Indian tribes has revealed the presence of globally shared haplotypes that are implicated in health and diseases in respective populations. The dendrogram based phylogenetic analyses have revealed the Caucasian affinity of Urali and palaeo-Mediterranean and Indo-European affinity of Malasar tribes. The presence of globally shared susceptible and protective haplotypes revealed the mosaic immunogenetic fabric of south Indian tribes.
PMID: 33359263 [PubMed - as supplied by publisher]

Source: Infection, Genetics and Evolution - December 22, 2020 Category: Genetics & Stem Cells Authors: Rangasamy N, Chinniah R, Vijayan M, Sivanadham R, Ravi PM, Darsa KV, Pandi S, Sevak V, Krishnan P, Karuppiah B Tags: Infect Genet Evol Source Type: research