Cell Biology: Size Scaling of Mitotic Spindles.
Cell Biology: Size Scaling of Mitotic Spindles.
Curr Biol. 2020 Dec 21;30(24):R1476-R1478
Authors: Mitchison TJ
Abstract
An investigation of how mitotic spindle size scales with cell size in early zebrafish embryos reveals fundamental principles of spindle organization. Spindle size depends primarily on microtubule number, which is regulated by a reaction-diffusion system when cells are large, and by signals from the plasma membrane when they are small.
PMID: 33352128 [PubMed - as supplied by publisher]
Source: Current Biology - Category: Biology Authors: Mitchison TJ Tags: Curr Biol Source Type: research