An update on the role of long non-coding RNAs in psoriasis.

An update on the role of long non-coding RNAs in psoriasis. Chin Med J (Engl). 2020 Dec 14;: Authors: Song JK, Yin SY, Li W, Li XD, Luo Y, Luo Y, Xing M, Li B, Kuai L Abstract Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating mechanisms and functions of lncRNAs in psoriasis, especially focusing on the role of lncRNAs in keratinocytes, T cells, and dendritic cells. PMID: 33323820 [PubMed - as supplied by publisher]
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research