New approaches for hydrogen therapy of various diseases.

New approaches for hydrogen therapy of various diseases.
Curr Pharm Des. 2020 Dec 10;:
Authors: Zhang L, Yu H, Tu Q, He Q, Huang N
Abstract
Hydrogen therapy has recently attracted increasing attention as an emerging and promising therapeutic technology due to its selective antioxidant properties and regulatory capacities in vivo. To effectively solve the low solubility issue of hydrogen, a variety of nanomaterials and devices for hydrogen supply have recently been developed, aiming to increase the concentration of hydrogen in specific disease location and realize controlled hydrogen release and combined treatment. In this review, we mainly focus on the latest advances in using hydrogen-generating devices and nanomaterials for hydrogen therapy. These developments include the sustained release of H2 , controlled release of H2 , and versatile modalities of synergistic therapy, etc. Also, bio-safety issues and challenges are discussed to further promote the clinical applications of hydrogen therapy and the development of hydrogen medicine.
PMID: 33308113 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - December 10, 2020 Category: Drugs & Pharmacology Authors: Zhang L, Yu H, Tu Q, He Q, Huang N Tags: Curr Pharm Des Source Type: research