Shared DNA methylation signatures in childhood allergy: the MeDALL study

Capsule Summary: This large-scale epigenome-wide meta-analysis identified 21 CpG sites in whole blood to be consistently associated with childhood allergic disease and implicates shared epigenetic mechanisms of asthma, rhinitis and eczema.

Source: Journal of Allergy and Clinical Immunology - December 15, 2020 Category: Allergy & Immunology Authors: Cheng-Jian Xu, Olena Gruzieva, Cancan Qi, Ana Esplugues, Ulrike Gehring, Anna Bergstr öm, Dan Mason, Leda Chatzi, Daniela Porta, Karin C. Lodrup Carlsen, Nour Baïz, Anne-Marie Madore, Harri Alenius, Bianca van Rijkom, Soesma A. Jankipersadsing, Pieter v Source Type: research