Impact of scaling up dolutegravir on antiretroviral resistance in South Africa: A modeling study

ConclusionsOur model shows the potential benefit of scaling up DTG-based regimens for halting the rise of NNRTI resistance. Starting or switching all men and women to DTG would lead to a sustained decline in resistance levels, whereas using DTG-based ART in all men, or in men and women beyond childbearing age, would only slow down the increase in levels of NNRTI PDR.
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research