Performance Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 PCR Tests in a Single Health System

The current pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the approval of numerous molecular diagnostic assays with various performance and technical capacities. There are limited data comparing performance among assays. We conducted a retrospective analysis of>10,000 test results among three widely used RT-PCR assays for coronavirus disease 2019 (CDC, Simplexa Direct, and TaqPath) to assess performance characteristics. We also retested remnant weakly positive specimens to assess analytical sensitivity.

https://www.jmdjournal.org/article/S1525-1578(20)30583-3/fulltext?rss=yes

Source: Journal of Molecular Diagnostics - December 4, 2020 Category: Pathology Authors: Travis K. Price, Brian C. Bowland, Sukantha Chandrasekaran, Omai B. Garner, Shangxin Yang Tags: Regular article Source Type: research