Measuring vital capacity in amyotrophic lateral sclerosis: Effects of interfaces and reproducibility

Deterioration of vital capacity (VC) in amyotrophic lateral sclerosis (ALS) signifies disease progression and indicates need for non-invasive ventilation. Weak facial muscles consequent to ALS, with resulting poor mouth seal, may interfere with the accuracy of VC measurements.

Source: Respiratory Medicine - December 3, 2020 Category: Respiratory Medicine Authors: Giulia Michela Pellegrino, Giuseppe Francesco Sferrazza Papa, Stefano Centanni, Massimo Corbo, David Kvarnberg, Martin J. Tobin, Franco Laghi Source Type: research