Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia

Activation of NF-kappaB RelA deacetylated at the lysine residues, except the lysine 310, drives pro-apoptotic transcription in noxious brain ischemia. We showed that the sinergistic combination of the histone ...

Source: Journal of Neuroinflammation - November 27, 2020 Category: Neurology Authors: Mariana Mota, Vanessa Porrini, Edoardo Parrella, Marina Benarese, Arianna Bellucci, Sina Rhein, Markus Schwaninger and Marina Pizzi Tags: Research Source Type: research