Ghost cell odontogenic carcinoma arising in the background of a calcifying odontogenic cyst

This report highlights an additional case of a GCOC arising from a pre-existing COC after 3  years in an adolescent male. The patient initially presented with a painless swelling of the right mandibular corpus. Panoramic radiographic examination showed an expansive unilocular radiolucent lesion. After 3 years, the radiographic features appeared more aggressive with increased expansion an d cortical perforation. A wide surgical resection was performed, whereby the lesion was diagnosed as a GCOC. Due to the rarity of these malignant neoplasms, limited information is available regarding their biological behaviour. One-year follow-up revealed no clinical signs of recurrence.
Source: Oral Radiology - Category: Radiology Source Type: research