Hydrocortisone decreases lethality and inflammatory cytokine and nitric oxide production in rats challenged with B. anthracis cell wall peptidoglycan

Lethal B. anthracis infection produces high proinflammatory peptidoglycan (PGN) burdens in hosts. We investigated whether the lethality and inflammation anthrax PGN can produce are related.

Source: Intensive Care Medicine Experimental - November 18, 2020 Category: Surgery Authors: Yan Li, Xizhong Cui, Joseph Shiloach, Jeffrey Wang, Dante A. Suffredini, Wanying Xu, Wancang Liu, Yvonne Fitz, Junfeng Sun and Peter Q. Eichacker Tags: Research Source Type: research