Cbx4 Regulates RNA Binding Protein MEX-3B To Thymic stromal lymphopoietin Expression Sumoylation In Epithelium Of HDM-induced Allergic Inflammation

Conclusion: CBX4/MEX-3B/TSLP axis involved in TSLP-mediated airway inflammation,suggesting that targeting SUMO E3 ligase activity of CBX4 would be a novel target for the treatment of asthma.

Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: shixiu, l., Changhui, Y., Zicong, Z., Zili, Z., Jieyi, L., Shaoxi, C. Tags: Allergy and immunology Source Type: research