Computational Analysis of Multidimensional Behavioral Alterations After Chronic Social Defeat Stress

The study of depression in humans depends on animal models that attempt to mimic specific features of the human syndrome. Most studies focus on one or a few behavioral domains, with time and practical considerations prohibiting a comprehensive evaluation. While machine-learning has enabled unbiased analysis of behavior in animals, this has not yet been applied to animal models of psychiatric disease.

Source: Biological Psychiatry - October 23, 2020 Category: Psychiatry Authors: Zachary S. Lorsch, Alberto Ambesi-Impiombato, Rebecca Zenowich, Irene Morganstern, Emer Leahy, Mukesh Bansal, Eric J. Nestler, Taleen Hanania Tags: Archival Report Source Type: research