Use of a carbonic anhydrase ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio).

In conclusion, while loss of Ca17a caused marked changes in ion uptake rates, providing strong evidence for a Ca17a-depedent Cl- uptake mechanism, the underlying causes of the lethality of this mutation in zebrafish remain unclear.
PMID: 33085911 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - October 21, 2020 Category: Physiology Authors: Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research