Should prolonged ceftriaxone infusions be preferred in septic patients?

We read with interest the article by Agunbiade et al. about ‘The effects of ceftriaxone by an intravenous push on adverse drug reactions in the emergency department’. Ceftriaxone intravenous push (IVP) decreases time of administration when compared with intravenous infusion (IVI). In addition, the rate of adverse reactions does not increase with IVP [1]. However, some efficacy concerns can arise, especially in sepsis and critically ill patients.

Source: The American Journal of Emergency Medicine - July 3, 2020 Category: Emergency Medicine Authors: Emre Kara, Melda Bahap, Ahmet Cagkan Inkaya Source Type: research