Regulation of SETD2 stability is important for the fidelity of H3K36me3 deposition

The histone H3K36me3 mark regulates transcription elongation, pre-mRNA splicing, DNA methylation, and DNA damage repair. However, knowledge of the regulation of the enzyme SETD2, which deposits this functional...

Source: Epigenetics and Chromatin - October 6, 2020 Category: Genetics & Stem Cells Authors: Saikat Bhattacharya and Jerry L. Workman Tags: Research Source Type: research