Evaluation of Transforming Growth Factor Beta 1 Expression in Ameloblastoma, Calcifying Odontogenic Cyst and Odontogenic Keratocyst

Conclusion: Reduced TGF-β1 immunoexpression in epithelial cells of ameloblastomas and COCs compared to OKCs could be associated with the primitive phenotype and more invasive biological behavior of these lesions. Reduced stromal expression of TGF-β1 in OK1Cs could be explained by its looser stroma than other studied lesions.

Source: Journal of Orofacial Sciences - June 11, 2020 Category: Dentistry Authors: Nasrollah Saghravanian Narges Ghazi Amirhosein Habibollahi Mohammad Taghi Shakeri Source Type: research