Three new p-coumaroylated sesquiterpenoids from Pilea cavaleriei.

Three new p-coumaroylated sesquiterpenoids from Pilea cavaleriei.
Nat Prod Res. 2020 Sep 30;:1-7
Authors: Zhou Y, Ren HC, Zhang QY, Liang H, Tu PF
Abstract
Four p-coumaroylated sesquiterpenoids (1-4), including three new ones (1, 2, and 4), were isolated from the whole plants of Pilea cavaleriei. Their structures were established on the basis of comprehensive spectroscopic analysis and comparison with data reported in the literature. Compounds 1-4 were evaluated for their antimycobacterial activities, and 2 and 4 were active against Mycobacterium tuberculosis H37Rv with the MIC values of 19.6 ± 0.19 and 17.4 ± 0.12 μg/mL, respectively.[Formula: see text].
PMID: 32993365 [PubMed - as supplied by publisher]

Source: Natural Product Research - September 29, 2020 Category: Biochemistry Authors: Zhou Y, Ren HC, Zhang QY, Liang H, Tu PF Tags: Nat Prod Res Source Type: research